IL10 Haplotype Associated with Tuberculin Skin Test Response but Not with Pulmonary TB

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IL10 Haplotype Associated with Tuberculin Skin Test Response but Not with Pulmonary TB

Evidence from genetic association and twin studies indicates that susceptibility to tuberculosis (TB) is under genetic control. One gene implicated in susceptibility to TB is that encoding interleukin-10 (IL10). In a group of 2010 Ghanaian patients with pulmonary TB and 2346 healthy controls exposed to Mycobacterium tuberculosis, among them 129 individuals lacking a tuberculin skin test (PPD) r...

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Comparison of sensitivity of QuantiFERON-TB gold test and tuberculin skin test in active pulmonary tuberculosis.

OBJECTIVE To compare the sensitivity of tuberculin skin test (TST) and quantiFERON-TB gold test (QFT-G) in active pulmonary tuberculosis. STUDY DESIGN Analytical study. PLACE AND DURATION OF STUDY Department of Pulmonology, Fauji Foundation Hospital, Rawalpindi, from July 2011 to January 2012. METHODOLOGY QuantiFERON-TB gold test (QFT-G) was evaluated and compared it with tuberculin skin ...

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Case-Control study of Firefighters with documented positive tuberculin skin test results using Quantiferon-TB testing in comparison with Firefighters with negative tuberculin skin test results

BACKGROUND Phoenix Firefighters have had abnormally high rates of tuberculin skin test (TBST) results on medical surveillance. The objectives of this study were to evaluate our firefighters using QuantiFERON-TB (QFT), comparing the results to their TBST results. METHODS Using QFT results obtained during the study, we compared previously positive TBST responders (Cases) to negative responders ...

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QuantiFERON-TB Gold and Tuberculin Skin Test for the Diagnosis of Latent Tuberculosis Infection in Children

Background: Appropriate diagnosis and treatment of latent tuberculosis infection (LTBI) play the most important role in the control of tuberculosis. This study aimed to determine the prevalence of LTBI among healthy tuberculosis unexposed children vaccinated with BCG using the tuberculin skin test (TST) and QuantiFERON TB Gold In-Tube (QFT-GIT) and comparing the agreement between the two tests....

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Tuberculin Skin Test Result and Risk of Death among Persons with Active TB

BACKGROUND Although the tuberculin skin test (TST) is frequently used to aid in the diagnosis of tuberculosis (TB) disease and to identify persons with latent TB infection, it is an imperfect test and approximately 10-25% of persons with microbiologically confirmed TB disease have a negative TST. Previous studies have suggested that persons with a negative TST are more likely to present with se...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2009

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0005420